PAK6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA534100-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA534100 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PAK6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pak6
Gene Alias
4732456M09; p21 (CDKN1A)-activated kinase 6; p21 (RAC1) activated kinase 6; p21 protein (Cdc42/Rac)-activated kinase 6; p21(CDKN1A)-activated kinase 6; p21-activated kinase 6; PAK5; PAK-5; PAK6; PAK-6; Serine/threonine-protein kinase PAK 6
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100071463, 100856038, 56924
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
Q9NQU5
Gene Symbols
Pak6
Immunogen
Synthetic 18 amino acid peptide from Linker domain of human PAK6.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Canine, Equine, Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Dog, Horse (100%) Goat, Elephant, Panda, Rabbit (94%)
- PAK6 is a serine/threonine kinase expressed in the testis and prostate
- It associates with both the estrogen and androgen receptors
- The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac
- They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding
- Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding
- The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility
- Much less is known about the second group, which includes PAK4, 5 and 6
- These proteins are not activated by Cdc42/Rac binding
- Later experiments have shown it to be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting that PAK6 may play a role in the cellular response to stress-related signals.