PACS1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA558589-Each-of-1 | In Stock | ₹ 51,397.50 |
PIPA558589 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,397.50
GST (18%): ₹ 9,251.55
Total Price: ₹ 60,649.05
Antigen
PACS1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PACS1
Gene Alias
AI325977; cytosolic sorting protein PACS-1; KIAA1175; LOW QUALITY PROTEIN: phosphofurin acidic cluster sorting protein 1; phosphofurin acidic cluster sorting protein 1; MRD17; PACS1; PACS-1; Phosphofurin acidic cluster sorting protein 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55690
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q6VY07
Gene Symbols
PACS1
Immunogen
Recombinant protein corresponding to Human PACS1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: DTTSPMELAA LEKIKSTWIK NQDDSLTETD TLEITDQDMF GDASTSLVVP EKVKTPMKSS KTDLQGSASP SKVEGVHTPR QKRSTPLKER QLSKPLSE Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 97%
- PACS-1 (CRA_a) is a 963 amino acid rich regulatory protein involved in protein trafficking and belongs to the PACS family
- A coat protein involved in controlling the correct subcellular localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs, PACS-1 is also known to be involved in HIV-1 Nef-mediated removal of MHC-I from the cell surface to the TGN, thus enabling HIV-1 to escape immune surveillance
- PACS-1 also controls the endosome to Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the adapter-protein complex-1 (AP-1) of endosomal clathrin coated membrane pits
- Usually seen in golgi apparatus, trans-Golgi network and localized in the paranuclear region, it is ubiquitously expressed in most of the tissues.