PIPA565219

IKBIP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA565219-Each-of-1 In Stock ₹ 52,332.00

PIPA565219 - Each of 1

₹ 52,332.00

In Stock

Quantity

1

Base Price: ₹ 52,332.00

GST (18%): ₹ 9,419.76

Total Price: ₹ 61,751.76

Antigen

IKBIP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IKBIP

Gene Alias

1200009F10Rik; 1700023M03Rik; D18354; I kappa B kinase interacting protein; i kappa-B kinase interacting protein; i kappa-B kinase-interacting protein; Ikbip; IKBKB interacting protein; IKBKB-interacting protein; Ikip; IKK interacting protein; IKK-interacting protein; inhibitor of nuclear factor kappa-B kinase-interacting protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

121457

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q70UQ0

Gene Symbols

IKBIP

Immunogen

Recombinant Human IKBIP

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: DSTLRNIRTVK RQEEEDLLRV EEQLGSDTKA IEKLEEEQHA LFARDEDLTN KLSDYEPKVE ECKTHLPTIE SAI Highest antigen sequence identity to the following orthologs - mouse 85%, rat 84%
  • IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1
  • APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions
  • The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis
  • IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane
  • IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell
  • The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.