PIPA578549
SELK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA578549-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA578549 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
SELK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SELENOK
Gene Alias
1110001C03Rik; AA673253; heat shock protein; heat shock protein, 30 kDa; Hsp30; HSPC030; HSPC297; Selenok; Selenoprotein K; SELK
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
58515
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.62 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
Q9Y6D0
Gene Symbols
SELENOK
Immunogen
Recombinant protein encompassing a sequence within the center region of human SELK. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: K562 Predicted Reactivity: Dog (97%), Pig (91%), Rabbit (89%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (89%) Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- SELK is a selenoprotein, containing a selenocysteine residue at its active site
- SELK is localized to the endoplasmic reticulum and is highly expressed in the heart, where it may function as an antioxidant
- SELK can bind to proteins such as the ER-associated degradation (ERAD) components p97 ATPase, Derlin-1 and -2, and SelS as well as proteins in the oligosaccharyltransferase complex, suggesting that SELK may be involved in the Derlin-dependent ERAD of glycosylated misfolded proteins
- SELK is also thought to be important in Ca2+ flux in immune cells, and is cleaved by m-calpain in resting macrophages
- When these macrophages are activated through different Toll-like receptors, this cleavage is inhibited.