SKP2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA578168-Each-of-1 | In Stock | ₹ 52,332.00 |
PIPA578168 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,332.00
GST (18%): ₹ 9,419.76
Total Price: ₹ 61,751.76
Antigen
SKP2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SKP2
Gene Alias
4930500A04Rik; CDK2/cyclin A-associated protein p45; cyclin A/CDK2-associated protein p45; Cyclin-A/CDK2-associated protein p45; FBL1; F-box protein Skp2; F-box/LRR-repeat protein 1; F-box/WD-40 protein 1; FBXL1; FLB1; FWD1; MGC1366; OTTHUMP00000221389; p45; p45skp2; RGD1562456; Skp2; S-phase kinase-associated protein 2; S-phase kinase-associated protein 2 (p45); S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6502
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.48 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
Q13309
Gene Symbols
SKP2
Immunogen
Full length human SKP2 recombinant protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: 293T, A431, HeLa, HepG2 Predicted Reactivity: Mouse (86%), Rat (88%), Pig (94%), Bovine (90%) Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Skp2 (S-phase Kinase-associated Protein 2) belongs to the family of F-box proteins that interact with the Cyclin A-Cdk2 complex
- Skp2 is essential for the G1-S transition in both transformed cells and diploid fibroblasts
- Biochemical and genetic experiments have demonstrated that Skp2 is required for the ubiquitination and consequent degradation of p27 in cultured mammalian cells and in vitro reconstitution assays
- In normal tissues, Skp2 is expressed in tonsil and placenta
- In tumor tissues, Skp2 is expressed widely, in some colon, prostate, pancreas, and skin cancers, with high expression in lung, breast, ovarian, and endometrial cancers
- Research suggests that Skp2 plays a role in oncogenesis, particularly in the pathogenesis of lymphomas and breast cancers.