alpha Synuclein Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA589182-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA589182 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
alpha Synuclein
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SNCA
Gene Alias
Alpha synuclein, alphaSYN, alpha-synuclein, NACP, non A-beta component of AD amyloid, non-A beta component of AD amyloid, non-A4 component of amyloid, Non-A4 component of amyloid precursor, PARK1, PARK4, PD1, Snca, Syn, synuclein alpha, synuclein alpha-140, synuclein, alpha, synuclein, alpha (non A4 component of amyloid precursor)
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20617, 29219, 6622
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2.05 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
O55042, P37377, P37840
Gene Symbols
SNCA
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 59-140 of human alpha-Synuclein (NP_0003361)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: TKEQVTNVGG AVVTGVTAVA QKTVEGAGSI AAATGFVKKD QLGKNEEGAP QEGILEDMPV DPDNEAYEMP SEEGYQDYEP EA Positive Samples: Rat brain; Cellular Location: Cell junction, Cytoplasm, Membrane, Nucleus, cytosol, synapse Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein
- These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking
- Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that they may also be involved in signaling pathways
- Defects in the SNCA gene, which encodes alpha-synuclein, have been implicated in the pathogenesis of Parkinson's disease
- Additionally, alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease
- Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene
- Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and Dementia, Lewy Body.