ACVR2A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596020-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA596020 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
ACVR2A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ACVR2A
Gene Alias
activin A receptor type 2A, activin A receptor type IIA, activin A receptor, type IIA, activin receptor IIA, activin receptor type IIA, Activin receptor type-2A, Actrii, ActrIIa, ACTR-IIA, ACVR2, Acvr2a, rActR-II, TactrII, type II activin receptor
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11480, 29263, 92
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.44 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
P27037, P27038, P38444
Gene Symbols
ACVR2A
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-140 of human ACVR2A (NP_0016071)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: SW480, Mouse kidney, Rat testis, Rat ovary; Cellular Location: Membrane, Single-pass type I membrane protein Immunogen sequence: AILGRSETQE CLFFNANWEK DRTNQTGVEP CYGDKDKRRH CFATWKNISG SIEIVKQGCW LDDINCYDRT DCVEKKDSPE VYFCCCEGNM CNEKFSYFPE MEVTQPTSNP VTPKPPYYNI L Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases
- ACVR2A is involved in the activin and myostatin signaling pathway
- (ACVR2A Aliases: ACVR2, ACTRII)
- These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity
- Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors
- Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors
- Type II receptors are considered to be constitutively active kinases.