TCP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA589190-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA589190 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
TCP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TCP1
Gene Alias
65 kDa antigen, AI528772, c-cpn, CCT, Cct1, Ccta, CCTalpha, CCT-alpha, chaperonin-containing T-complex alpha subunit TCP1, chaperonin-containing T-complex polypeptide alpha subunit, cytosolic chaperonin containing t-complex polypeptide 1, D6S230E, hypothetical protein, p63, tailless complex polypeptide 1, tailless complex polypeptide 1A, Tailless complex polypeptide 1B, t-complex 1, t-complex polypeptide 1, t-complex protein 1, T-complex protein 1 alpha subunit-like protein, T-complex protein 1 subunit alpha, T-complex protein 1 subunit alpha A, T-complex protein 1 subunit alpha B, T-complex protein 1, alpha subunit, Tcp1, Tcp-1, TCP-1-A, TCP-1-alpha, TCP-1-B, Tp63, TRic, Unknown (protein for MGC:133746), YD8142.13, YD8142B.04, YDR212W
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
21454, 24818, 6950
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.48 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P11983, P17987, P28480
Gene Symbols
TCP1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 307-556 of human TCP1 (NP_1103792)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: AVRRVLKRDL KRIAKASGAT ILSTLANLEG EETFEAAMLG QAEEVVQERI CDDELILIKN TKARTSASII LRGANDFMCD EMERSLHDAL CVVKRVLESK SVVPGGGAVE AALSIYLENY ATSMGSREQL AIAEFARSLL VIPNTLAVNA AQDSTDLVAK LRAFHNEAQV NPERKNLKWI GLDLSNGKPR DNKQAGVFEP TIVKVKSLKF ATEAAITILR IDDLIKLHPE SKDDKHGSYE DAVHSGALND; Positive Samples: U-251MG, 293T, PC-3, Jurkat; Cellular Location: Cytoplasm, centrosome, cytoskeleton, microtubule organizing center The T Complex Polypeptide 1 (TCP-1) is approximately 60 kDa protein constitutively expressed in almost all eukaryotic cells, and is upregulated during spermatogenesis
- It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin
- The family of proteins termed chaperonins act to recognize and stabilize polypeptide intermediates during folding, assembly and disassembly, and share many characteristics with Heat Shock Protein 70 (HSP70) including high abundance, induction by environmental stress, and ATPase activity
- The chaperonin family includes the mitochondrial HSP60, Escherichia coli GroEL, the plastid Rubisco-subunit binding protein, and the archaebacterial protein TF55
- The TCP-1 sequence shows nearly 40% identity to TF55, but only minimal similarity to HSP60 and GroEL.