PIPA596109

UHRF1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA596109-Each-of-1 In Stock ₹ 47,036.50

PIPA596109 - Each of 1

₹ 47,036.50

In Stock

Quantity

1

Base Price: ₹ 47,036.50

GST (18%): ₹ 8,466.57

Total Price: ₹ 55,503.07

Antigen

UHRF1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

UHRF1

Gene Alias

Ac2-121, AL022808, E3 ubiquitin-protein ligase UHRF1, fb97f09, FLJ21925, hNP95, Hnp95 Huhrf1, hUHRF1, HuNp95, ICBP90, inverted CCAAT box-binding protein of 90 kDa, Liver regeneration-related protein LRRG126, MGC138707, mUhrf1, Np95, nuclear phosphoprotein 95, nuclear protein, nuclear protein 95, Nuclear zinc finger protein Np95, RING finger protein 106, RING-type E3 ubiquitin transferase UHRF1, RNF106, TDRD22, transcription factor ICBP90, ub, ubiquitin like with PHD and ring finger domains 1, ubiquitin-like PHD and RING finger domain-containing protein 1, ubiquitin-like with PHD and ring finger domains 1, ubiquitin-like, containing PHD and RING finger domains, 1, ubiquitin-like-containing PHD and RING finger domains protein 1, Uhrf1, unm b1115, unm_b1115, wu:fb97f09, zgc:63539

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18140, 29128

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.57 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

Q8VDF2, Q96T88

Gene Symbols

UHRF1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human UHRF1 (NP_0010416661)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MWIQVRTMDG RQTHTVDSLS RLTKVEELRR KIQELFHVEP GLQRLFYRGK QMEDGHTLFD YEVRLNDTIQ LLVRQSLVLP HSTKERDSEL SDTDSGCCLG QSESDKSSTH GEAAAETDSR PADEDMWDET ELGLYKVNEY VDARDTNMGA WFEAQVVRVT RKAPSRDEPC SSTSRPALEE DVIYHVKYDD YPENGVVQMN SRDVRARART IIKWQDLEVG QVVMLNYNPD NPKERGFWYD AEISRKRETR TARELYANVV; Positive Samples: THP-1, HeLa, SW480, MCF7; Cellular Location: Nucleus This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases
  • The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression
  • Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle
  • It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint
  • Multiple transcript variants encoding different isoforms have been found for this gene.