SUMO1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596065-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA596065 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
SUMO1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SUMO1
Gene Alias
CG4494-PA, DAP1, GAP modifying protein 1, GAP-modifying protein 1, GMP1, LD07775p, OFC10, OK/SW-cl.43, OTTHUMP00000202403, OTTHUMP00000202404, OTTHUMP00000202405, OTTHUMP00000202406, OTTHUMP00000202409, OTTHUMP00000202410, PIC1, SENP2, sentrin, Sentrin-1, small ubiquitin-like modifier 1, small ubiquitin-related modifier 1, small ubiquitin-related modifier-1, SMT3, SMT3 homolog 3, SMT3 suppressor of mif two 3 homolog 1, SMT3 suppressor of mif two 3 homolog 1 (yeast), Smt3C, Smt3h3, SMTP3, Sumo1, SUMO-1, SUMO-1 related peptidase, Ubiquitin-homology domain protein PIC1, ubiquitin-like 1, ubiquitin-like 1 (sentrin), ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1, UBL1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22218, 301442, 7341
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Concentration
1.28 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P63165, P63166, Q5I0H3
Gene Symbols
SUMO1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human SUMO1 (NP_0033431)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MSDQEAKPST EDLGDKKEGE YIKLKVIGQD SSEIHFKVKM TTHLKKLKES YCQRQGVPMN SLRFLFEGQR IADNHTPKEL GMEEEDVIEV YQEQTGGHST V; Positive Samples: HeLa, A-431, NCI-H460, SW480, Mouse brain, Mouse liver, Mouse testis, Rat brain, Rat testis; Cellular Location: Cell membrane, Cytoplasm, Nucleus, Nucleus membrane, Nucleus speckle, PML body SUMO1 is an ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer
- Covalent attachment, via an isopeptide bond, to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4
- This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction
- SUMO1 is involved, for instance, in targeting RANGAP1 to the nuclear pore complex protein RANBP2
- Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins
- SUMO1 may also regulate a network of genes involved in palate development
- Mutations in the gene can result in non-syndromic orofacial cleft 10.