CD1d Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA589255-Each-of-1 | In Stock | ₹ 46,413.50 |
PIPA589255 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
CD1d
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CD1D
Gene Alias
AI747460, Antigen-presenting glycoprotein CD1d, antigen-presenting glycoprotein CD1d1, Cd1, CD1.1, CD1A, Cd1d, CD1D antigen, CD1D antigen, d polypeptide, CD1d molecule, CD1d.1, Cd1d1, CD1d1 antigen, CD1d1 molecule, differentiation antigen CD1-alpha-3, HMC class I antigen-like glycoprotein CD1D, Ly-38, R3, R3G1, T-cell surface glycoprotein CD1d, T-cell surface glycoprotein CD1d1, thymocyte antigen CD1D
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12479, 912
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot, Immunohistochemistry, Western Blot
Concentration
1.16 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P11609, P15813
Gene Symbols
CD1D, Cd1d1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human CD1D (NP_0017571)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: EVPQRLFPLR CLQISSFANS SWTRTDGLAW LGELQTHSWS NDSDTVRSLK PWSQGTFSDQ QWETLQHIFR VYRSSFTRDV KEFAKMLRLS YPLELQVSAG CEVHPGNASN NFFHVAFQGK DILSFQGTSW EPTQEAPLWV NLAIQVLNQD KWTRETVQWL LNGTCPQFVS G; Positive Samples: Mouse liver; Cellular Location: Cell membrane, Endosome membrane, Lysosome membrane, Single-pass type I membrane protein CD1d is a heavy chain associated with Beta 2 microglobulin on cortical thymocytes
- Beta 2 microglobulin independent expression of CD1d has also been demonstrated on human intestinal epithelial cells
- CD1d is the sole group 2 member of the CD1 family of major histocompatibility (MHC) like glycoproteins
- The CD1d gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin
- The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells
- The human genome contains five CD1 family genes organized in a cluster on chromosome 1
- The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands
- The protein encoded by the CD1d gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail
- Diseases associated with CD1D include Mycobacterium Malmoense and Autoimmune Disease.