CD150 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596046-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA596046 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CD150
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Slamf1
Gene Alias
4933415F16, AA177906, CD150, CD150 antigen, CDw150, ESTM51, IPO-3, RGD1560634, signaling lymphocyte activation molecule, signaling lymphocytic activation molecule, signaling lymphocytic activation molecule family member 1, Slam, SLAM family member 1, Slamf1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
27218, 6504
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.62 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q13291, Q9QUM4
Gene Symbols
Slamf1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 21-237 of human CD150/SLAM (NP_0030281)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: ASYGTGGRMM NCPKILRQLG SKVLLPLTYE RINKSMNKSI HIVVTMAKSL ENSVENKIVS LDPSEAGPPR YLGDRYKFYL ENLTLGIRES RKEDEGWYLM TLEKNVSVQR FCLQLRLYEQ VSTPEIKVLN KTQENGTCTL ILGCTVEKGD HVAYSWSEKA GTHPLNPANS SHLLSLTLGP QHADNIYICT VSNPISNNSQ TFSPWPGCRT DPSETKP; Positive Samples: Jurkat, Mouse liver; Cellular Location: Cell membrane, Single-pass type I membrane protein CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation
- SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation
- Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM
- It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells
- Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells
- Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain
- Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).