Carbonic Anhydrase IX Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA589358-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA589358 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Carbonic Anhydrase IX
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CA9
Gene Alias
Ca9, CA-9, CAIX, CA-IX, Car9, Carbonate dehydratase IX, carbonic anhydrase 9, Carbonic anhydrase IX, carbonic dehydratase, G250, Membrane antigen MN, membrane antigen MN homolog, MN, MN/CA9, P54 / 58N, P54/58N, pMW1, RCC-associated antigen G250, RCC-associated protein G250, renal cell carcinoma-associated antigen G250
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
230099, 313495, 768
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.02 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q16790, Q8VHB5
Gene Symbols
CA9, Car9
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 52-151 of human Carbonic Anhydrase 9 (CA9/G250) (NP_0012072)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: GSSGEDDPLG EEDLPSEEDS PREEDPPGEE DLPGEEDLPG EEDLPEVKPK SEEEGSLKLE DLPTVEAPGD PQEPQNNAHR DKEGDDQSHW RYGGDPPWPR; Positive Samples: Mouse small intestine, Rat small intestine; Cellular Location: Cell membrane, Cell projection, Nucleus, Single-pass type I membrane protein, microvillus membrane, nucleolus Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions
- It is abundant in all mammalian tissues
- There are many genes that are inducible by hypoxia, via HIF-1 alpha
- CA IX is one of the most inducible genes because of its stability and location within the membrane
- Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux
- The pH is important in cell death under hypoxia, thus a blockade of CA IX results in increased cell death under hypoxia
- Therefore, CA IX has become a reliable histochemical marker of hypoxia.