PIPA595694
CAB39 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595694-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA595694 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CAB39
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CAB39
Gene Alias
AA408805, AA960512, C78372, Cab39, calcium binding protein 39, calcium binding protein, 39 kDa, calcium-binding protein 39, CGI-66, MO25, MO25alpha, Protein Mo25
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12283, 301574, 51719
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1.16 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q06138, Q9Y376
Gene Symbols
CAB39
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-341 of human CAB39 (NP_0573731)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: U-87MG; Cellular Location: Cytoplasm Immunogen sequence: MPFPFGKSHK SPADIVKNLK ESMAVLEKQD ISDKKAEKAT EEVSKNLVAM KEILYGTNEK EPQTEAVAQL AQELYNSGLL STLVADLQLI DFEGKKDVAQ IFNNILRRQI GTRTPTVEYI CTQQNILFML LKGYESPEIA LNCGIMLREC IRHEPLAKII LWSEQFYDFF RYVEMSTFDI ASDAFATFKD LLTRHKLLSA EFLEQHYDRF FSEYEKLLHS ENYVTKRQSL KLLGELLLDR HNFTIMTKYI SKPENLKLMM NLLRDKSRNI QFEAFHVFKV FVANPNKTQP ILDILLKNQA KLIEFLSKFQ NDRTEDEQFN DEKTYLVKQI RDLKRPAQQE A Peutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer
- The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS
- LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha)
- STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1
- The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK).