IQSEC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595835-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA595835 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
IQSEC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IQSEC1
Gene Alias
ADP-ribosylation factors guanine nucleotide-exchange protein 100, ADP-ribosylation factors guanine nucleotide-exchange protein 2, ARFGEP100, ARF-GEP100, AW561907, BC026481, BRAG2, brefeldin A-resistant ARF-GEF2, brefeldin-resistant Arf-GEF 2 protein, cI-43, D6Ertd349e, GEP100, IQ motif and Sec7 domain 1, IQ motif and SEC7 domain-containing protein 1, Iqsec1, Kiaa0763
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
232227, 686590
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.25 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q8R0S2
Gene Symbols
IQSEC1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human IQSEC1 (NP_0556843)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: mouse brain, rat brain Immunogen sequence: SFEGPEKVHS SYFEGKQVSV TNDGSQLGAL VSPECGDLSE PTTLKSPAPS SDFADAITEL EDAFSRQVKS LAESIDDALN CRSLHTEEAP ALDAARARDT EPQTALHGMD HRKLDEMTAS YSDVTLYIDE EELSPPLPLS QAGDRPSSTE SDLRLRAGGA APDYWALAHK EDKADTDTSC RSTPSLERQE QRLRVEHLPL L ADP ribosylation factors (Arfs) are small GTP-binding proteins known for their role in vesicular transport, where they nucleate the assembly of coat protein complexes at sites of carrier vesicle formation
- IQSEC1 (GEP100/BRAG2), a guanine nucleotide exchange protein for ARF6, belongs to the BRAG family and contains one IQ domain, one PH domain and one SEC7 domain
- As a known activator of ARF6, IQSEC1 regulates cell surface levels of Beta1 integrin and its knockdown blocked tumour metastasis
- IQSEC1 links EGFR signaling to ARF6 activation and may contribute to the cancer metastasis and malignancy.