IPO5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596023-Each-of-1 | In Stock | ₹ 47,036.50 |
PIPA596023 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,036.50
GST (18%): ₹ 8,466.57
Total Price: ₹ 55,503.07
Antigen
IPO5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IPO5
Gene Alias
1110011C18Rik, 5730478E03Rik, AA409333, C76941, IMB3, imp5, importin 5, importin beta-3 subunit, importin subunit beta-3, Importin-5, IPO 5, IPO5, karyopherin (importin) beta 3, Karyopherin beta 3, karyopherin beta-3, Kpnb3, MGC2068, Pse1, RAN binding protein 5, Ran_GTP binding protein 5, ran-binding protein 5, RanBP 5, Ranbp5
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
306182, 3843, 70572
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
3.31 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
O00410, Q8BKC5
Gene Symbols
IPO5
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human IPO5 (NP_0022623)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: AAAAAEQQQF YLLLGNLLSP DNVVRKQAEE TYENIPGQSK ITFLLQAIRN TTAAEEARQM AAVLLRRLLS SAFDEVYPAL PSDVQTAIKS ELLMIIQMET QSSMRKKVCD IAAELARNLI DEDGNNQWPE GLKFLFDSVS SQNVGLREAA LHIFWNFPGI FGNQQQHYLD VIKRMLVQCM QDQEHPSIRT LSARATAAFI LANEHNVALF KHFADLLPGF LQAVNDSCYQ NDDSVLKSLV EIADTVPKYL RPHLEATLQL SLKLCGDTSL NNMQRQLALE V; Positive Samples: SW620, HeLa, 293T, HepG2, Mouse testis, Mouse brain; Cellular Location: Cytoplasm, Nucleus, nucleolus Excitation: 405 nm; Emission: 645 nm; Laser: Blue Laser Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope
- The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins
- Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex
- In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate
- Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore
- Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex
- The protein encoded by this gene is a member of the importin beta family.