MRC2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA597268-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA597268 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
MRC2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MRC2
Gene Alias
CD280, CLEC13E, collagen-binding factor Endo180, C-type lectin domain family 13 member E, C-type mannose receptor 2, Endo180, endocytic receptor (macrophage mannose receptor family), endocytic receptor 180, KIAA0709, Lectin lambda, macrophage mannose receptor 2, mannose receptor C type 2, mannose receptor, C type 2, mKIAA0709, Mrc2, novel lectin, UPARAP, UPAR-associated protein, urokinase-type plasminogen activator receptor-associated protein
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17534, 9902
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.6 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q64449, Q9UBG0
Gene Symbols
MRC2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 120-300 of human MRC2 (NP_0060302)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: RWHCRTLGDQ LSLLLGARTS NISKPGTLER GDQTRSGQWR IYGSEEDLCA LPYHEVYTIQ GNSHGKPCTI PFKYDNQWFH GCTSTGREDG HLWCATTQDY GKDERWGFCP IKSNDCETFW DKDQLTDSCY QFNFQSTLSW REAWASCEQQ GADLLSITEI HEQTYINGLL TGYSSTLWIG L; Positive Samples: SH-SY5Y, HeLa, Mouse kidney; Cellular Location: Membrane, Single-pass type I membrane protein May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity
- Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis
- May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface
- May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices
- May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover
- May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).