MTF2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596571-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA596571 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
MTF2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Mtf2
Gene Alias
9230112N11Rik, AA537621, C76717, dJ976O13.2, hPCl2, M96, Metal regulatory transcription factor 2, metal response element binding transcription factor 2, metal response element DNA-binding protein M96, metal response element-binding transcription factor 2, metal-response element DNA-binding protein M96, Metal-response element-binding transcription factor 2, mPCl2, MTF2, PCL2, polycomb-like 2, polycomb-like protein 2, putative DNA binding protein, RGD1304727, RP5-976O13.1, TDRD19A, tudor domain containing 19A, zinc-regulated factor 1, ZiRF1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17765, 22823, 360905
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.24 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q02395, Q9Y483
Gene Symbols
Mtf2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MTF2 (NP_0011578641)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MRDSTGAGNS LVHKRSPLRR NQKTPTSLTK LSLQDGHKAK KPACKFEEGQ DVLARWSDGL FYLGTIKKIN ILKQSCFIIF EDSSKSWVLW KDIQTGATGS GEMVCTICQE EYSEAPNEMV ICDKCGQGYH QLCHTPHIDS SVIDSDEKWL CRQCVFATTT KRGGALKKGP NAKALQVMKQ TLPYSVADLE; Positive Samples: HL-60, HepG2, Mouse brain, Rat brain; Cellular Location: Nucleus Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex
- Acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex, leading to enhance PRC2 H3K27me3 methylation activity
- Regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation
- Promotes recruitment of the PRC2 complex to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells
- Required to repress Hox genes by enhancing H3K27me3 methylation of the PRC2 complex
- In some conditions may act as an inhibitor of PRC2 activity: able to activate the CDKN2A gene and promote cellular senescence by suppressing the catalytic activity of the PRC2 complex locally
- Binds to the metal-regulating-element (MRE) of MT1A gene promoter