PIPA599534

LIMK1/LIMK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599534-Each-of-1 In Stock ₹ 46,502.50

PIPA599534 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

LIMK1/LIMK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LIMK1

Gene Alias

KIZ-1, LIM domain kinase 1, LIM domain kinase 2, lim kinase 1, LIM kinase 2, LIM motif-containing protein kinase, LIM motif-containing protein kinase 1, LIM motif-containing protein kinase 2, LIM-domain containing protein kinase 1, LIM-domain containing, protein kinase, LIM-domain containing, protein kinase 1, Limk, LIMK 2, LIMK1, LIMK-1, LIMK2, LIMK-2, Limk2b, Link2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16885, 16886, 29524, 3984, 3985, 65172

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O54785, P53667, P53668, P53669, P53670, P53671

Gene Symbols

LIMK1, LIMK2

Immunogen

A synthesized peptide derived from human LIMK1(Accession P53667), corresponding to amino acid residues A482-V532.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total LIMK1/2
  • Proteins containing LIM motifs are typically involved in cell fate determination and growth control
  • A family of proteins designated LIM kinases, including LIMK-1 and LIMK-2, has been identified
  • LIMK-1 has been shown to regulate the stabilization of F-Actin structures and cofilin activity, indicating that LIMK-1 plays a role in a signaling pathway involved in the regulation of cell motility and morphogenesis
  • LIMK-1 inhibits neuronal differentiation of PC12 cells, and is thought to act by interfering with events downstream of MAPK activation
  • Expression patterns of LIMK-1 and LIMK-2 suggest that these proteins may have different functions during development
  • A truncated form of LIMK-2 has been identified in adult testis that is thought to arise from an alternative initiation exon.