PIPA599539

SMAD2/SMAD3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599539-Each-of-1 In Stock ₹ 46,502.50

PIPA599539 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

SMAD2/SMAD3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SMAD3

Gene Alias

7120426M23Rik; AU022421; hMAD-2; hMAD-3; hSMAD2; hSMAD3; HSPC193; HsT17436; JV15-2; JV18; JV18-1; LDS1C; LDS3; MAD (mothers against decapentaplegic, Drosophila) homolog 3; MAD homolog 2; MAD homolog 3; mad homolog JV15-2; mad protein homolog; MAD, mothers against decapentaplegic homolog 3; mad3; MADH2; MADH3; MADR2; mad-related protein 2; mMad2; mMad3; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic homolog 3; mothers against DPP homolog 2; mothers against DPP homolog 3; pSMAD2; Sma- and Mad-related protein 2; SMA- and MAD-related protein 3; SMAD; Smad 2; Smad 3; SMAD family member 2; SMAD family member 3; SMAD, mothers against DPP homolog 2; SMAD, mothers against DPP homolog 3; Smad2; Smad-2; Smad3

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17126, 17127, 25631, 29357, 4087, 4088

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O70436, P84022, P84025, Q15796, Q62432, Q8BUN5

Gene Symbols

SMAD2, SMAD3

Immunogen

A synthesized peptide derived from human SMAD3(Accession P84022), corresponding to amino acid residues M1-E32.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total Smad2/3
  • Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling
  • Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and Activin-mediated growth modulation
  • Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members
  • Smad6 and Smad7 regulate the response to Activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad proteins.