Phospho-TrkC (Tyr705) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA599562-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA599562 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
Phospho-TrkC (Tyr705)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ntrk3
Gene Alias
AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18213, 29613, 4916
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q03351, Q16288, Q6VNS1
Gene Symbols
Ntrk3
Immunogen
A synthesized peptide derived from human NTRK3(Accession Q16288), corresponding to amino acid residues around phosphorylated Tyr705.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of TrkC only when phosphorylated at Tyr705
- NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system
- Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1
- The different isoforms do not have identical signaling properties
- The protein is widely expressed, mainly in the nervous tissue
- The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain
- TRKC is subject to ligand-mediated auto-phosphorylation
- The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.