PK110950UL
MilliporeSigma™ anti-PhosphoDetect Src Family (pTyr416), Polyclonal
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PK110950UL-Each-of-1 | In Stock | ₹ 36,490.00 |
PK110950UL - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,490.00
GST (18%): ₹ 6,568.20
Total Price: ₹ 43,058.20
Antigen
PhosphoDetect™ Src Family (pTyr416)
Classification
Polyclonal
Formulation
In 150mM NaCl, 10mM sodium HEPES, 100μg/mL BSA, 50% glycerol, pH 7.5.
Immunogen
a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr416phosphorylation site of human Src
Regulatory Status
RUO
Test Specificity
Recognizes the ∽60kDa Src protein phosphorylated at Tyr416in COLO 201 cells and PDGF-treated NIH/3T3 cells. May also recognize other Src family kinases phosphorylated at equivalent sites.
Content And Storage
−20°C
Isotype
IgG
Applications
Immunoblot
Conjugate
Unconjugated
Host Species
Rabbit
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Chicken, Human, Mouse, Rat, Xenopus species
Form
Purified
Related Products
Description
- Specifically detects PhosphoDetect™ Src Family (pTyr 416 ) Clone: in Chicken, Human, Mouse, Rat, Xenopus samples, and it is validated for Immuno Blotting The Scr family of protein kinases, including Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, plays an important role in the regulation of growth and differentiation of eukaryotic cells
- Lck is essential for T-cell activation and differentiation
- Phosphorylation of Tyr 505 in the C-terminal tail results in downregulation of enzyme activity, while phosphorylation of Tyr 394 results in an upregulation of activity
- Lyn is predominantly expressed in hematopoietic cells and is important in signaling from multiple cell surface receptors, such as the B cell receptor (BCR) and CD40.