ST10291SET
MilliporeSigma™ anti-PhosphoDetect Fos (pSer374) Clone: 340000,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ST10291SET-Each-of-1 | In Stock | ₹ 67,571.47 |
ST10291SET - Each of 1
In Stock
Quantity
1
Base Price: ₹ 67,571.47
GST (18%): ₹ 12,162.865
Total Price: ₹ 79,734.335
Antigen
Fos (pSer374)
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
1 Set
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Applications
ELISA, Immunoblot, Immunoblot
Clone
340000
Formulation
100μg antibody lyophilized from 2X PBS, PEG, sucrose and 200μL lyophilized control lysate from EGF-treated HEPG2 cells.
Immunogen
a synthetic phosphopeptide corresponding to amino acids surrounding the Ser374phosphorylation site of human c-Fos
Regulatory Status
RUO
Test Specificity
Recognizes the ∽55kDa c-Fos protein phosphorylated at Ser374. Does not detect the unphosphorylated form.
Content And Storage
−20°C
Isotype
IgG1
Related Products
Description
- Specifically detects Fos (pSer 374 ) Clone: 340000 in Human samples, and it is validated for ELISA, Immuno Blotting The early gene product c-Fos is expressed following mitogenic stimulation and functions as a sensor for MAPK signal duration
- When MAPK activation is transient, MAPK activity declines before accumulation of the c-Fos protein
- When MAPK activation is sustained, c-Fos is phosphorylated by MAPK at Ser 374
- Phosphorylation stabilizes the Fos protein and primes c-Fos for additional phosphorylation at Thr 325 .