7161599
Tocris Bioscience™ Avagacestat
Highly potent γ-secretase inhibitor; orally bioavailable
Manufacturer: Fischer Scientific
CAS Number: 1146699-66-2
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Chemical Name or Material
(2R)-2-[[(4-Chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide
Synonym
BMS-708163
Formula Weight
520.89
CAS
1146699-66-2
Molecular Formula
C20H17ClF4N4O4S
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ Avagacestat | -- | ₹ 35,617.80 | ||
Tocris Bioscience™ Avagacestat | -- | ₹ 9,291.60 | ||
Apexbio Technology LLC BMS-708163 (Avagacestat), 2mg. Cas: 1146699-66-2 MFCD: MFCD13195458. γ-secretase inhibitor | -- | ₹ 7,031.00 | ||
Selleck Chemical LLC Avagacestat (BMS-708163) 5mg 1146699-66-2 | -- | ₹ 18,156.00 | ||
Pentanamide, 2-[[(4-chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoro-, (2R)- | -- | ₹ 1,780.00 - ₹ 29,014.00 | ||
Avagacestat | -- | ₹ 6,408.00 - ₹ 85,440.00 |
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Description
- Highly potent γ-secretase inhibitor (Aβ40 IC50 = 0.3 nM) Exhibits >137-fold selectivity for amyloid-β precursor protein (APP) processing over Notch Reduces plasma and brain Aβ40 and Aβ42 levels in vivo Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C