7161633
Tocris Bioscience™ Ibrutinib
Potent and selective BTK inhibitor (IC50= 0.5 nM)
Manufacturer: Fischer Scientific
CAS Number: 936563-96-1
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Chemical Name or Material
1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one
Synonym
Agammaglobulinaemia tyrosine kinase, AGMX1, ATKIMD1, B-cell progenitor kinase, BPK, Bruton agammaglobulinemia tyrosine kinase, Bruton tyrosine kinase, dominant-negative kinase-deficient Brutons tyrosine kinase, tyrosine-protein kinase
Formula Weight
440.5
CAS
936563-96-1
Molecular Formula
C25H24N6O2
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Selleck Chemical LLC Ibrutinib (PCI-32765) 5mg 936563-96-1 | -- | ₹ 18,156.00 | ||
Tocris Bioscience™ Ibrutinib | -- | ₹ 19,936.00 | ||
Tocris Bioscience™ Ibrutinib | -- | ₹ 82,058.00 | ||
Medchemexpress LLC HY-10997 100mg , Ibrutinib CAS:936563-96-1 Purity:>98% | -- | ₹ 10,092.60 | ||
Medchemexpress LLC HY-10997 500mg , Ibrutinib CAS:936563-96-1 Purity:>98% | -- | -- | ||
Apexbio Technology LLC PCI-32765 (Ibrutinib), 50mg. Cas: 936563-96-1 MFCD: MFCD20261150. Bruton's tyrosine kinase (BTK) inhibitor | -- | ₹ 21,360.00 | ||
eMolecules Ambeed / (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[34-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one / 10mg / 534566703 / A150396 / / 936563-96-1 / MFCD20261150 / 440.507 / C25H24N6O2 | -- | ₹ 2,148.46 | ||
Medchemexpress LLC HY-10997 200mg Medchemexpress, Ibrutinib CAS:936563-96-1 Purity:>98% | -- | ₹ 12,335.40 | ||
Selleck Chemical LLC Ibrutinib (PCI-32765) 10mM/1mL 936563-96-1 | -- | ₹ 29,049.60 | ||
Ibrutinib | -- | ₹ 1,068.00 - ₹ 52,065.00 |
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Description
- Selective for BTK against a screening panel of kinase enzymes Inhibits autophosphorylation of BTK, phosphorylation of PLCγ, and phosphorylation of ERK (IC50 of 11 nM, 29 nM and 13 nM, respectively) Induces cytotoxicity of chronic lymphocytic leukemia (CLL) cells Reduces clinical arthritis scores in a mouse model.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C