7235753

Tocris™ Conduritol B epoxide

Irreversible glucocerebrosidase (β-glucosidase) inhibitor; used to generate Gaucher disease models

Manufacturer: Fischer Scientific

CAS Number: 6090-95-5

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Chemical Name or Material

DL-1,2-Anhydro-myo-Inositol

CAS

6090-95-5

Target

Glycosylase Inhibitors

Molecular Formula

C6H10O5

Other Options

Image Product Name Manufacturer Price Range
Tocris™ Conduritol B epoxide
-- ₹ 50,374.00
Tocris™ Conduritol B epoxide
-- ₹ 12,727.00
Enzo Life Sciences Conduritol B Epoxide (25 mg). CAS: 6090-95-5
-- ₹ 31,830.85
eMolecules​ Conduritol B Epoxide | 6090-95-5 | | 250mg
-- ₹ 41,579.91
Conduritol B epoxide
-- ₹ 17,471.55 - ₹ 62,308.70
Conduritol B epoxide
-- ₹ 16,910.00 - ₹ 76,985.00

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Description

  • Conduritol B epoxide is an irreversible glucocerebrosidase (GBA) inhibitor (Ki = 53 μM; IC50 = 4.28 - 9.49 μM)
  • Also inhibitis lysosomal α-glucosidase
  • Used to generate animal models of Gaucher disease
  • Accelerates recovery of peripheral nerve injury in mice
  • Preserves motoneurons and ganglioside distribution at the neuromuscular junction, delays disease onset and improves motor function in a mouse ALS model.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C