T144
(±)-Thalidomide
≥98%, powder
Manufacturer: Sigma Aldrich
CAS Number: 50-35-1
Synonym(S): (±)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | T144-100-MG | In Stock | ₹ 10,410.00 |
| 1 G | T144-1-G | In Stock | ₹ 59,970.00 |
T144 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 10,410.00
GST (18%): ₹ 1,873.80
Total Price: ₹ 12,283.80
ligand
thalidomide
Assay
≥98%
form
powder
reaction suitability
reagent type: ligand
color
white
solubility
DMSO: 20 mg/mL, clear
originator
Celgene
SMILES string
O=C1CCC(N2C(=O)c3ccccc3C2=O)C(=O)N1
InChI
1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)
InChI key
UEJJHQNACJXSKW-UHFFFAOYSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
eMolecules Ambeed / 2-(26-Dioxopiperidin-3-yl)isoindoline-13-dione / 1mg / 713090201 / A164079 / / 50-35-1 / MFCD00153873 / 258.233 / C13H10N2O4 | -- | ₹ 2,148.46 | ||
Sigma Aldrich Fine Chemicals Biosciences Thalidomide United States Pharmacopeia (USP) Reference Standard | 50-35-1 | MFCD00153873 | 200MG | -- | ₹ 56,604.00 | ||
Thalidomide | -- | ₹ 48,398.58 | ||
Thalidomide | -- | ₹ 16,194.20 | ||
Thalidomide | -- | ₹ 5,340.00 - ₹ 10,680.00 |
Related Products
Description
- Application: Thalidomide has been used to study its neuropathological effects in mouse models of Alzheimer′s disease (AD). This study reported that long term administration of thalidomide causes beta-secretase inhibition and subsequently alleviates amyloid-like pathology[1]. Furthermore, thalidomide has also been used to evaluate its teratogenic functions. Thalidomide was found to affect endodermal differentiation and neural development in differentiating human embryonic and induced pluripotent stem cells[2].
- Biochem/physiol Actions: (±)-Thalidomide selectively inhibits biosynthesis of tumor necrosis factor α (TNF-α). It also functions as an inhibitor of angiogenesis, an immunosuppressive agent, a sedative and a teratogen. Furthermore, thalidomide is known to exhibit antitumor functions in refractory multiple myeloma[3].
- Features and Benefits: This compound was developed by Celgene. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
- Preparation Note: Thalidomide is soluble in DMSO at a concentration that is more than 20 mg/ml. It is insoluble in water and ethanol.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P202 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P362 + P364
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Repr. 1A
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves