860539P
C16 Glucosyl(β) Ceramide (d18:1/16:0)
Manufacturer: Sigma Aldrich
CAS Number: 74365-77-8
Synonym(S): D-glucosyl-β-1,1′-N-palmitoyl-D-erythro-sphingosine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | 860539P-5-MG | In Stock | ₹ 29,638.85 |
860539P - 5 MG
In Stock
Quantity
1
Base Price: ₹ 29,638.85
GST (18%): ₹ 5,334.993
Total Price: ₹ 34,973.843
form
powder
packaging
pkg of 1 × 25 mg (860539P-25mg)pkg of 1 × 5 mg (860539P-5mg)
manufacturer/tradename
Avanti Polar Lipids
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
74365-77-8 | 1-O-β-D-Glucopyranosyl-N-hexadecanoylsphingosine | -- | ₹ 22,161.00 |
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Description
- General description: Glucosyl(β) Ceramide (β-GlcCer) is a naturally occurring glycolipid and an ubiquitous intracellular metabolite.[1][2] It might be present in the endoplasmic reticulum or Golgi apparatus.[1]
- Application: C16 Glucosyl(β) Ceramide (d18:1/16:0) or D-glucosyl-β-1,1′-N-palmitoyl-D-erythro-sphingosine has been used as a stock solution for the in vitro treatment of bacteria and to study the role of sphingolipids on pulmonary Pseudomonas aeruginosa infections in cystic fibrosis (CF).[3] It may be used in the quantification of lipid in green fluorescence protein (GFP) and fatty acid transport protein 4 (FATP4) cells using electrospray ionization tandem mass spectrometry (ESI-MS/MS).[4]
- Biochem/physiol Actions: Glucosyl(β) Ceramide (β-GlcCer) is an endogenous macrophage inducible C-type lectin (Mincle) ligand, which has immunostimulatory property. It also stimulates inflammatory and acquired immune responses on myeloid cells through Mincle. It is a potential biomarker in Gaucher′s disease.[1] β-GlcCer regulates the function of natural killer T (NKT) lymphocytes and exhibits antimetastatic effects.[2][5] A balanced level of intracellular β-GlcCer is essential for maintaining tissue homeostasis.[1]
- Packaging: 5 mL Amber Glass Screw Cap Vial (860539P-25mg)