7166772

Tocris™ LY 2955303

High affinity and selective RARγ antagonist

Manufacturer: Fischer Scientific

CAS Number: 1433497-19-8

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Chemical Name or Material

4-[5-[3,5-Bis(1,1-dimethylethyl)phenyl]-1-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-1H-pyrazol-3-yl]benzoic acid

Solubility

Soluble to 20 mM in DMSO

Formula Weight

578.74

Purity

98%

CAS

1433497-19-8

Molecular Formula

C36H42N4O3

Product Type

Antagonist

Other Options

Image Product Name Manufacturer Price Range
Tocris™ LY 2955303
-- ₹ 9,905.70
Tocris™ LY 2955303
-- ₹ 37,246.50
Sigma Aldrich Fine Chemicals Biosciences LY2955303 >=98% (HPLC) | 1433497-19-8 | MFCD31561443 | 5MG
-- ₹ 11,448.07
1433497-19-8 | LY2955303
-- ₹ 2,581.00 - ₹ 30,527.00

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Description

  • High affinity and selective RARγ antagonist (K i values are 1.1 nM, >1.7 μM and >2.9 μM for RARγ, RARα and RARβ respectively)
  • Displays analgesic efficacy in a mouse model of osteoarthritis-like joint pain.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C