78-261-0
Tocris Bioscience™ Sonidegib
Manufacturer: Fischer Scientific
CAS Number: 956697-53-3
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Chemical Name or Material
rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide
Quantity
10 mg
Molecular Formula
C26H26F3N3O3
CAS
956697-53-3
Target
Smoothened
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ Sonidegib | -- | -- | ||
Tocris Bioscience™ Sonidegib | -- | ₹ 1,01,727.00 | ||
Enzo Life Sciences Sonidegib (free base) (25mg). CAS: 956697-53-3 | -- | ₹ 33,161.40 | ||
Enzo Life Sciences Sonidegib (free base) (500mg). CAS: 956697-53-3 | -- | ₹ 2,78,422.26 | ||
Enzo Life Sciences Sonidegib (free base) (100mg). CAS: 956697-53-3 | -- | ₹ 90,708.80 | ||
Enzo Life Sciences Sonidegib (free base) (50mg). CAS: 956697-53-3 | -- | ₹ 54,408.37 | ||
Selleck Chemical LLC Sonidegib (NVP-LDE225) 25mg 956697-53-3 Erismodegib | -- | ₹ 49,359.40 | ||
eMolecules Erismodegib | 956697-53-3 | | 50mg | -- | ₹ 26,374.26 | ||
Medchemexpress LLC HY-16582A 10mg Medchemexpress, Sonidegib CAS:956697-53-3 Purity:>98% | -- | ₹ 8,597.40 | ||
Enzo Life Sciences Sonidegib (free base) (10mg). CAS: 956697-53-3 | -- | ₹ 18,423.00 |
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Description
- Sonidegib is a potent Smoothened (Smo) receptor antagonist (IC50 values are 1.3 nM and 2.5 nM at mouse and human receptors, respectively)
- Inhibits growth of a variety of tumor types including basal cell carcinoma, small cell lung cancer and medulloblastoma
- Sonidegib inhibits Hh pathway in CD34+ chronic myeloid leukemia cells; it reduces both the number of cells and self-renewal ability
- Brain penetrant and orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.