78-265-0

Tocris Bioscience™ Sonidegib

Manufacturer: Fischer Scientific

CAS Number: 956697-53-3

Select a Size

Pack Size SKU Availability Price
Each of 1 78-265-0-Each-of-1 In Stock ₹ 1,01,727.00

78-265-0 - Each of 1

₹ 1,01,727.00

In Stock

Quantity

1

Base Price: ₹ 1,01,727.00

GST (18%): ₹ 18,310.86

Total Price: ₹ 1,20,037.86

Chemical Name or Material

rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide

Quantity

50 mg

Molecular Formula

C26H26F3N3O3

CAS

956697-53-3

Target

Smoothened

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ Sonidegib
-- --
Tocris Bioscience™ Sonidegib
-- --
Enzo Life Sciences Sonidegib (free base) (25mg). CAS: 956697-53-3
-- ₹ 33,161.40
Enzo Life Sciences Sonidegib (free base) (500mg). CAS: 956697-53-3
-- ₹ 2,78,422.26
Enzo Life Sciences Sonidegib (free base) (100mg). CAS: 956697-53-3
-- ₹ 90,708.80
Enzo Life Sciences Sonidegib (free base) (50mg). CAS: 956697-53-3
-- ₹ 54,408.37
Selleck Chemical LLC Sonidegib (NVP-LDE225) 25mg 956697-53-3 Erismodegib
-- ₹ 49,359.40
eMolecules​ Erismodegib | 956697-53-3 | | 50mg
-- ₹ 26,374.26
Medchemexpress LLC HY-16582A 10mg Medchemexpress, Sonidegib CAS:956697-53-3 Purity:>98%
-- ₹ 8,597.40
Enzo Life Sciences Sonidegib (free base) (10mg). CAS: 956697-53-3
-- ₹ 18,423.00

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Description

  • Sonidegib is a potent Smoothened (Smo) receptor antagonist (IC50 values are 1.3 nM and 2.5 nM at mouse and human receptors, respectively)
  • Inhibits growth of a variety of tumor types including basal cell carcinoma, small cell lung cancer and medulloblastoma
  • Sonidegib inhibits Hh pathway in CD34+ chronic myeloid leukemia cells; it reduces both the number of cells and self-renewal ability
  • Brain penetrant and orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.