7112423

Tocris Bioscience™ Cinacalcet hydrochloride

Low molecular weight, organic compound that may help regulate biological process.

Manufacturer: Fischer Scientific

CAS Number: 364782-34-3

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Product Type

Inhibitor

CAS

364782-34-3

Formula Weight

393.87g/mol

For Use With (Application)

Calcium-Sensing Receptor Agonists

Target Proteins

Calcium-Sensing Receptor

Molecular Formula

C22H22F3N.HCl

Content And Storage

Store at -20°C

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Description

  • Calcium-sensing receptor (CaSR) allosteric agonist
  • Activates CaSR signaling in cellular proliferation and phosphatidylinositol (PI) hydrolysis assays
  • Reduces serum parathyroid hormone levels in rats
  • Also potent CYP2D2 inhibitor (IC50 = 87 nM) and L-type calcium channel blocker
  • Orally bioavailable.