59-815-0

Tocris Bioscience™ Itraconazole

Manufacturer: Tocris Bioscience™

CAS Number: 84625-61-6

Select a Size

Pack Size SKU Availability Price
Each of 1 59-815-0-Each-of-1 In Stock ₹ 8,766.50

59-815-0 - Each of 1

₹ 8,766.50

In Stock

Quantity

1

Base Price: ₹ 8,766.50

GST (18%): ₹ 1,577.97

Total Price: ₹ 10,344.47

Chemical Name or Material

4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one

Quantity

50 mg

Molecular Formula

C35H38Cl2N8O4

Purity

>99%

CAS

84625-61-6

Target

Smoothened Receptor Antagonists

Formula Weight

705.63

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Description

  • Itraconazole is a SMO antagonist (IC50 = 690 nM); acts at different binding site to cyclopamine (Cat
  • No
  • 1623)
  • Also cytochrome p450 inhibitor (IC50 = 16-26 nM)
  • Inhibits cell cycle at G1 phase in vitro and blocks angiogenesis in vivo (IC50 = 160 nM)
  • Antifungal.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C