01-674-164
DNase II Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-164-Each-of-1 | In Stock | ₹ 47,170.00 |
01-674-164 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,170.00
GST (18%): ₹ 8,490.60
Total Price: ₹ 55,660.60
Antigen
DNase II
Classification
Polyclonal
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O00115
Gene Symbols
DNASE2
Immunogen
Synthetic peptide corresponding to residues 347-360 of human DNase II precursor.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
DNASE2
Gene Alias
DNASE2A, DNL, DNL2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1777
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- A suggested positive control for this product is human spleen lysate
- Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation
- These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins including AIF and Acinus
- DNase II causes both chromatin condensation and DNA fragmentation
- The genes encoding human, porcine, and murine DNase II have been cloned
- The DNase II gene encodes a 40 kDa proenzyme
- The mature enzyme consists of two non-identical subunits, the 32 kDa (a) and 12 kDa (b) chains, generated by proteolytic processing
- Overexpression of DNase II induces chromatin condensation (3)
- DNase II is ubiquitously expressed in human tissues.