01-675-024
ECM1 Monoclonal Antibody (SC-05), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-675-024-Each-of-1 | In Stock | ₹ 38,982.00 |
01-675-024 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,982.00
GST (18%): ₹ 7,016.76
Total Price: ₹ 45,998.76
Antigen
ECM1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
Q16610
Gene Symbols
ECM1
Immunogen
Affinity-purified secretory component from human colostrum.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
SC-05
Conjugate
Unconjugated
Gene
ECM1
Gene Alias
AI663821; ECM1; Extracellular matrix protein 1; LOW QUALITY PROTEIN: extracellular matrix protein 1; extracellular matrix protein 1; p85; RP11-54A4.6; Secretory component p85; testicular tissue protein Li 61; URBWD
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1893
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- This antibody reacts with 80 kDa human secretory component glycoprotein (both free and bound in secretory IgA)
- ECM1, also referred to as extracellular matrix protein 1, is a protein that plays a significant role in regulating extracellular matrix organization and cell adhesion
- It is expressed in various tissues, including the skin, lung, and liver, and is involved in the development and progression of several diseases, including cancer and dermatological disorders
- The protein interacts with several extracellular matrix proteins, such as collagen and fibronectin, and is involved in the regulation of cell proliferation, migration, and invasion
- ECM1 is also involved in endochondral bone formation, angiogenesis, and tumor biology
- It interacts with various extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis
- Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae, and certain viscera
- Different isoforms of ECM1 have been described in alternatively spliced transcript variants
- Diseases associated with ECM1 include Lipoid Proteinosis Of Urbach And Wiethe and Lichen Sclerosus Et Atrophicus.