01-676-186
STIM1 Monoclonal Antibody (CDN3H4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-186-Each-of-1 | In Stock | ₹ 47,659.50 |
01-676-186 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,659.50
GST (18%): ₹ 8,578.71
Total Price: ₹ 56,238.21
Antigen
STIM1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P70302, P84903, Q13586
Gene Symbols
STIM1
Immunogen
Synthetic peptide corresponding to the C-terminal cytoplasmic part of STIM1
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
CDN3H4
Conjugate
Unconjugated
Gene
STIM1
Gene Alias
D11S4896E; GOK; IMD10; RGD:1306831}; SIM; Stim1; stim1 {ECO:0000312; STIM1L; STRMK; Stromal interaction molecule 1; stromal interaction molecule 1 precursor; TAM; TAM1
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
20866, 361618, 6786
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- Western Blot: Both reducing and non-reducing conditions; Immunocytochemistry: Methanol-acetone fixation
- STIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane
- Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm
- However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet
- Many questions also remain to be solved around STIM1 functional distribution
- It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.