Vimentin Monoclonal Antibody (VI-01), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-675-938-Each-of-1 | In Stock | ₹ 53,489.00 |
01-675-938 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,489.00
GST (18%): ₹ 9,628.02
Total Price: ₹ 63,117.02
Antigen
Vimentin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 15mM sodium azide; pH 8
Gene Accession No.
P02543, P08670, P20152, P31000
Gene Symbols
Vim
Immunogen
Pellet of pig brain cold stable proteins after depolymerization of Microtubules.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mammalia, Mouse, Porcine, Rat
Product Type
Antibody
Isotype
IgM
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
VI-01
Conjugate
Unconjugated
Gene
Vim
Gene Alias
cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus
Host Species
Mouse
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100522394, 22352, 7431, 81818
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- Immunocytochemistry: Staining technique: (a) fix cells for 10 min in methanol at -20°C and for 6 min in acetone at -20°C; (b) fix cells directly in methanol for 10 min at -20°C or in acetone for 10 min at -20°C
- Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin
- It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane
- Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development
- During the development process, vimentin is exchanged for new, tissue-specific IFPs
- Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets
- Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event
- This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.