01-676-075
Vimentin Monoclonal Antibody (VI-RE/1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-075-Each-of-1 | In Stock | ₹ 44,366.50 |
01-676-075 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,366.50
GST (18%): ₹ 7,985.97
Total Price: ₹ 52,352.47
Antigen
Vimentin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P08670, P20152
Gene Symbols
Vim
Immunogen
Bacterially expressed full-length human vimentin
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
VI-RE/1
Conjugate
Unconjugated
Gene
Vim
Gene Alias
cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
22352, 7431
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- This antibody will not cross-react with porcine or mouse
- Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin
- It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane
- Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development
- During the development process, vimentin is exchanged for new, tissue-specific IFPs
- Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets
- Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event
- This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.