AFP Monoclonal Antibody (AFP-11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-098-Each-of-1 | In Stock | ₹ 29,236.50 |
01-676-098 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,236.50
GST (18%): ₹ 5,262.57
Total Price: ₹ 34,499.07
Antigen
AFP
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P02771
Gene Symbols
AFP
Immunogen
Purified alpha Fetoprotein.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Radioimmune Assays (RIA), Western Blot
Clone
AFP-11
Conjugate
Unconjugated
Gene
AFP
Gene Alias
a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
174
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- The MA1-19342 anti-alpha Fetoprotein antibody (clone AFP-11) has successfully been paired as the coating antibody in a sandwich ELISA with detection antibody MA1-19178 (clone AFP-01)
- Immunohistochemistry (Paraffin): Heat mediated antigen retrieval (sodium citrate buffer); mAb incubation 1 hour / RT, detection DAB; Western Blot: non-reducing conditions
- AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life
- AFP expression in adults is often associated with hepatoma or teratoma
- However, hereditary persistence of AFP may also be found in individuals with no obvious pathology
- The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4
- AFP is found in monomeric, dimeric, and trimeric forms
- AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin
- The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly
- High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.