200020167

PCSK9 Monoclonal Antibody (C5), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

PCSK9

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

AI415265, AI747682, convertase subtilisin, convertase subtilisin/kexin type 9 preproprotein, FH3, HCHOLA3, hypercholesterolemia, LDLCQ1, NARC1, NARC-1, neural apoptosis regulated convertase 1, neural apoptosis-regulated convertase 1, OTTHUMP00000009833, PC9, PCSK9, Proprotein convertase 9, proprotein convertase PC9, proprotein convertase subtilisin/kexin type 9, PSEC0052, Subtilisin/kexin-like protease PC9

Gene Symbols

PCSK9

Isotype

IgG2b κ

Purification Method

Protein A/G

Gene

PCSK9

Clone

C5

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Rat

Gene Accession No.

P59996

Gene ID (Entrez)

298296

Immunogen

Recombinant Rat PCSK9 protein, Trp164-Phe428 (Accession #P59996)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family
  • This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum
  • The protein may function as a proprotein convertase
  • The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.