PRDX2 Monoclonal Antibody (C2), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PRDX2
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
AL022839, Band-8, Calpromotin, epididymis secretory sperm binding protein Li 2a, HEL-S-2a, HGNC:9353, MGC4104, Natural killer cell-enhancing factor B, NkefB, NKEF-B, peroxiredoxin 2, peroxiredoxin-2, Prdx2, protector protein, PRP, Prx II-1, PRX2, PRXII, PTX1, Tdpx1, TDX1, thiol specific antioxidant protein, thiol-specific antioxidant 1, thiol-specific antioxidant protein, thioredoxin dependent peroxide reductase 1, thioredoxin peroxidase 1, thioredoxin reductase, thioredoxin-dependent peroxide reductase 1, Torin, TPx, TPX1, TPx-B, TR, Trx dependent peroxide reductase 1, TSA
Gene Symbols
PRDX2
Isotype
IgG1 κ
Purification Method
Protein A/G
Gene
PRDX2
Clone
C2
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human, Rat
Gene Accession No.
P32119, P35704
Gene ID (Entrez)
29338, 7001
Immunogen
Recombinant Human PRDX2 protein, Ala2-Asn198 (Accession #P32119)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Related Products
Description
- Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis
- Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms
- Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx
- Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system
- Mammalian Prxs are 20 - 30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.