PIK3C2B Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PIK3C2B
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Rat
Gene Alias
C2-PI3K, C330011J12Rik, Gm199, phosphatidylinositol 3-kinase C2 domain-containing beta polypeptide, phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta, phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta, phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta, phosphoinositide 3-kinase-C2-beta, phosphoinositide-3-kinase, class 2, beta polypeptide, pi3kc2b, PI3KC2beta, PI3K-C2beta, PI3K-C2-beta, PIK3C2B, PTDINS-3-kinase C2 beta, ptdIns-3-kinase C2 subunit beta
Gene Symbols
PIK3C2B
Isotype
IgG
Purification Method
Protein A
Gene
PIK3C2B
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene ID (Entrez)
289021
Immunogen
Recombinant Rat PIK3C2b protein, Ser790-Leu1025 (Accession #D3ZVF3)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Related Products
Description
- The Class II PI3 kinases, including PIK3C2B, phosphorylate the 3 position of PI or PI4P
- Though not as well studied as the class I PI3 kinases, the class II enyzmes have been linked to diverse, receptor-mediated cellular processes including insulin signaling, neuronal survival, and growth factor signaling
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein
- By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation
- With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes
- The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.