MMP1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
MMP1
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Goat, Human, Mouse, Ovine, Porcine
Gene Accession No.
P03956, P21692, Q9EPL5
Gene ID (Entrez)
101120355, 102170620, 397320, 4312, 83995
Immunogen
Recombinant Mouse MMP1 protein, Ala98-Pro275 (Accession #Q9EPL5)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
22 kDa interstitial collagenase, 27 kDa interstitial collagenase, CLG, CLGN, Collagenase, collagenase-like A, fibroblast collagenase, Interstitial collagenase, interstitial collagenase A, matrix metallo protease, matrix metallopeptidase 1, matrix metallopeptidase 1 (interstitial collagenase), matrix metallopeptidase 1a, matrix metallopeptidase 1a (interstitial collagenase), matrix metalloprotease 1, matrix metalloproteinase 1, matrix metalloproteinase 1a (interstitial collagenase), Matrix metalloproteinase1, Matrix metalloproteinase-1, Matrix metalloproteinase-1a, McolA, Mcol-A, MMP, MMP1, MMP-1, Mmp1a, MMP-1a, MMPs
Gene Symbols
MMP1, Mmp1a
Isotype
IgG
Purification Method
Protein A
Gene
MMP1
Related Products
Description
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis
- Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases
- This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III
- The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3
- Alternative splicing results in multiple transcript variants.