Fibrinogen Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Fibrinogen
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Porcine
Gene Accession No.
P14460, P14477
Gene ID (Entrez)
100514354, 100626178, 403164
Immunogen
Native Pig FG protein (Accession #P14460 & P14477)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
2510049G14Rik, 3010002H13Rik, A-alpha fibrinogen, Ab1-181, Ab1-216, Ac1-581, Ac1873, AI256424, carboxy-terminal region, ENSMUSG00000059807, epididymis secretory sperm binding protein Li 78p, Fba5e, Fga, Fgb, Fgg, Fib, Fib2, fibg, fibrinogen, fibrinogen A-alpha chain, fibrinogen A-alpha-chain, fibrinogen alpha chain, fibrinogen alpha-E subunit, fibrinogen beta chain, Fibrinogen gamma chain, fibrinogen gamma polypeptide, fibrinogen gamma-B chain, fibrinogen gamma-chain, fibrinogen, A alpha polypeptide, fibrinogen, alpha polypeptide, fibrinogen, B beta polypeptide, fibrinogen, beta polypeptide, fibrinogen, gamma polypeptide, Fibrinopeptide A, Fibrinopeptide B, Gamma', gamma-fibrinogen, HEL-S-78p, Liver regeneration-related protein LRRG036/LRRG043/LRRG189, MGC119422, MGC119423, MGC119425, PRO2061, testicular tissue protein Li 70, Unknown (protein for MGC:127951)
Gene Symbols
FGA, FGB, FGG
Isotype
IgG
Purification Method
Protein A
Related Products
Description
- Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates
- Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots
- Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments
- The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin
- Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.