Prohibitin Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Prohibitin
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse, Porcine, Rat
Gene Accession No.
P35232, P67778, P67779
Gene ID (Entrez)
100524707, 18673, 25344, 5245
Immunogen
Recombinant Human PHB protein, Met1-Gln272 (Accession #P35232)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
BAP 32, Bap32, B-cell receptor-associated protein 32, epididymis luminal protein 215, epididymis secretory sperm binding protein Li 54e, fa18f07, fb09f05, HEL-215, HEL-S-54e, OTTHUMP00000165765, OTTHUMP00000165766, OTTHUMP00000220103, OTTHUMP00000220170, OTTHUMP00000220171, PHB, phb protein, PHB1, Prohibitin, sr:nyz128, wu:fa18f07, wu:fb09f05
Gene Symbols
PHB
Isotype
IgG
Purification Method
Protein A
Gene
PHB
Related Products
Description
- Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed
- It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor
- Mutations in PHB have been linked to sporadic breast cancer
- Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region
- The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.