PSA Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PSA
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Mouse, Porcine, Rat
Gene Accession No.
P00756, P00758
Gene ID (Entrez)
18050, 24594
Immunogen
Recombinant Mouse PSA protein, His39-Pro261 (Accession #P00756)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
Antigen, antigen, prostate specific, APS, Fletcher factor, gamma-seminoprotein, hK3, Kal3, Kal-3, Kallikrein 3, kallikrein 3, plasma, kallikrein B, plasma 1, kallikrein related peptidase 3, kallikrein-3, Kallikrein-3 (KLK3), kallikrein-related peptidase 3, Kalp1, KALP15, Kininogenin, KLK2A1, Klk3, KLK-3, Klkb1, P-30 antigen, Pk, Plasma kallikrein, Plasma kallikrein heavy chain, Plasma kallikrein light chain, Plasma prekallikrein, prostate specific antigen, prostate-specific (APS), prostate-specific antigen, PSA, Semenogelase, seminin
Gene Symbols
Klk1b3
Isotype
IgG
Purification Method
Protein A
Gene
Klk1b3
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Description
- PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and is abundant in seminal fluid
- PSA can be detected in the sera of patients with prostatic carcinoma
- It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT)
- A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia
- PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics.