4544909

Epredia™ Lab Vision™ CD8 Rabbit Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry applications with Epredia™ CD8, Rabbit Monoclonal Antibody.

Manufacturer: Fischer Scientific

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Antigen

CD8

Applications

Immunohistochemistry (Paraffin)

Host Species

Rabbit

Research Discipline

T-Cell

Primary or Secondary

Primary

Clone

SP16

Classification

Monoclonal

Regulatory Status

IVD

Immunogen

Synthetic peptide sequence comprising the 13 C-terminal amino acids of the cytoplasmic domain of alpha chain of the CD8 molecule

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Description

  • CD8 molecule consists of two chains, termed α and β chain, which are expressed as a disulphide-linked α/β heterdimer or as an α/α homodimer on T cell subset, thymocytes and NK cells
  • The majority of CD8+ T cells express CD8 as α/β heterdimer
  • CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex
  • The HIV-2 envelope glycoprotein binds CD8 alpha chain (but not β chain)
  • Host Species: Rabbit Clone: SP16 Species Reactivity: Human
  • Others not tested
  • Epitope: C-terminus Immunogen: Synthetic peptide sequence comprising the 13 C-terminal amino acids of the cytoplasmic domain of α-chain of the CD8 molecule Positive Control: Tonsil Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin)