4547013
CD117/c-Kit/SCF-Receptor Rabbit Polyclonal Antibody, Epredia™
Optimize staining of formalin-fixed, paraffin-embedded tissues with Epredia™ CD117/c-Kit/SCF-Receptor, Rabbit Polyclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
CD117/c-Kit/SCF-Receptor
Classification
Polyclonal
Host Species
Rabbit
Immunogen
A synthetic peptide from the cytoplasmic domain of human CD117 / c-kit protein
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Regulatory Status
IVD
Primary or Secondary
Primary
Related Products
Description
- Recognizes a protein of 145kDa, which is identified as CD117/p145kit
- This rabbit polyclonal antibody does not interfere with the binding of SCF to c-kit
- It precipitates both the unoccupied as well as the occupied form of c-kit
- The binding of the stem cell factor (SCF) to the c-kit-encoded receptor tyrosine kinase (Type III) stimulates a variety of biochemical responses that culminate in cellular proliferation, migration, or survival
- C-kit plays an important role in hematopoiesis, melanogenesis, and gametogenesis
- This antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues
- Host Species: Rabbit Isotype: IgG Species Reactivity: Human and Dog
- Others not tested Epitope: Cytoplasmic domain Immunogen: A synthetic peptide from the cytoplasmic domain of human CD117/c-kit protein Molecular Weight: 145 kDa Positive Control: Stromal tumor, skin or tonsil Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin)