50-173-7118

TRIB3 Mouse anti-Human, Mouse, Rat, Clone: 2C10C7, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-7118-Each-of-1 In Stock ₹ 44,150.23

50-173-7118 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

TRIB3

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

Q8K4K2, Q96RU7, Q9WTQ6

Gene Symbols

TRIB3

Immunogen

TRIB3 Fusion Protein Ag25776

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

2C10C7

Conjugate

Unconjugated

Gene

TRIB3

Gene Alias

C20orf97, NIPK, SINK, SKIP3, TRB 3, TRB3, TRIB3, Tribbles homolog 3

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

228775, 246273, 57761

Content And Storage

-20°C

Form

Liquid

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Description

  • A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis
  • Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity
  • TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family
  • Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA
  • TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.