7144525
BTBD12 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
BTBD12
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae), KIAA1784, KIAA1987, MUS312, SLX4, FANCP, BTBD12
Gene Symbols
SLX4
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q8IY92
Gene ID (Entrez)
84464
Immunogen
Between 1784 and 1834
Primary or Secondary
Primary
Content And Storage
4° C
Gene
SLX4
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee This gene encodes a structure-specific endonuclease subunit
- The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94
- The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure
- The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.